HEALTH KNOWLEDGE
AND BEAUTY

According to the cosmetic dictionary, Acetyl-hexapeptide-8, also known as Agireline, is a synthetic peptide compound used in skin care and makeup. Like other peptides, Acetyl-hexapeptide-8 contains water bonds, so it moisturizes the skin and restores skin damage.

About the history of formation:

Acetyl Hexapeptide-8 is an ingredient derived from the great research of Professor R. Bruce Merrifield of Rockefeller University. In 1949 he discovered peptide growth factors, further research led him to synthesize Peptides and finally with the idea for solid phase synthesis of peptides in 1959.

In 1984, he was awarded the Nobel Prize in Chemistry for developing a simple and ingenious method for obtaining peptides and proteins. Merrifield's method is a completely new approach to organic synthesis.

Based on that result, Acetyl Hexapeptide-8 was researched and released 10 years later. The birth of Acetyl Hexapeptide-8 is a great step forward in the cosmetics industry as this is the first Peptide and has a specific effect in reducing wrinkles. Today, Acetyl Hexapeptide-8 anti-aging cosmetics continue to be researched, developed and applied in many types of beauty cosmetics.

Acetyl-hexapeptide-8 is a peptide that has the ability to affect nerve impulses. When applied to wrinkled skin, Acetyl-hexapeptide-8 will interfere with the formation or stability of essential protein complexes used in the control process. Ca-dependent exocytosis2+, specifically here is cell moisture complex (also known as SNAPE). Through that, Acetyl-hexapeptide-8 inhibited the release of hormones belonging to the Catecholamine group (including 3 similar hormones: Dopamine, Adrenaline and Norepinephrine), a group of hormones that regulate emotions produced from the Adrenal Medulla.

To put it simply, Acetyl-hexapeptide-8 blocked messages that control muscle contractions from the brain to muscle groups in the skin area that this compound affects.

Thanks to this intervention mechanism, Acetyl-hexapeptide-8 has the ability to reduce the depth of facial wrinkles caused by facial muscle contraction, especially in 3 key skin areas: Eye area, forehead skin and skin around the mouth.

Acetyl-hexapeptide-8 for skin 

Science has conducted many studies on the wrinkle removal effect of Acetyl-hexapeptide-8, below is some information for your reference:

The benefits are proven

Acetyl-hexapeptide-8 has been shown to moisturize the skin, reducing wrinkles both in depth and width. Tests performed on healthy female volunteers showed that 10% Acetyl-hexapeptide-8 reduced wrinkle depth after 30 days of treatment.

Acetyl-hexapeptide-8 is not toxic because it does not penetrate deep into the internal skin structure, even after a few hours if used in cream form. In emulsion form, due to more hydration (Hydration), Acety-hexapeptide-8 is able to penetrate deeper into the skin. For this reason, choosing a wrinkle removal product must also be based on the finished product structure (cream or liquid).

Acetyl-hexapeptide-8 is considered a safe ingredient that can replace Botox in the future. In particular, Acetyl-hexapeptide-8 is most effective with Treatment of eye wrinkles

According to the scientific evidence provided above, we can see that Acetyl-hexapeptide-8 is a popular and safe ingredient in skin care products. The effect of Acetyl-hexapeptide-8 is most effective in: Reduce eye wrinkles and the quick response ability of Acetyl-hexapeptide-8 has also been shown by many studies.

The effect of Acetyl-hexapeptide-8 on reducing wrinkles depends on the state in the product, so using it in cream form is better and safer than liquid form. Acetyl-hexapeptide-8 is considered by the scientific community to have the potential to replace Botox in the future. 

However, besides those interesting benefits, Acetyl-hexapeptide-8 is not a magic compound to solve all problems of wrinkles and skin aging, especially aging at the structural layer. Acetyl-hexapeptide-8 is also contraindicated for sensitive skin, sunburn, allergies and people with neurological problems.

Hopefully the content we provide is useful to readers, helping readers take one step forward in their journey to discover the secrets of skin and products that support beauty care and preserve youth. Thank you very much for your interest!!!